Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Revenues:
Revenues	$ 1,524,485	$ 941,293	$ 3,039,592	$ 1,799,728
Costs and expenses:
Cost of sales	184,520	135,740	347,017	230,832
Research and development expenses	420,928	379,091	869,456	718,581
Sales, general and administrative expenses	191,804	156,502	374,062	303,547
Change in fair value of contingent consideration	9,200	0	10,800	0
Total costs and expenses	806,452	671,333	1,601,335	1,252,960
Income from operations	718,033	269,960	1,438,257	546,768
Interest income	4,243	18,076	16,819	33,691
Interest expense	(13,871)	(14,837)	(28,007)	(29,705)
Other income, net	116,365	53,939	55,235	96,549
Income before (benefit from) provision for income taxes	824,770	327,138	1,482,304	647,303
(Benefit from) provision for income taxes	(12,500)	59,711	42,281	111,245
Net income	$ 837,270	$ 267,427	$ 1,440,023	$ 536,058
Net income per common share:
Basic (in dollars per share)	$ 3.22	$ 1.04	$ 5.54	$ 2.09
Diluted (in dollars per share)	$ 3.18	$ 1.03	$ 5.46	$ 2.06
Shares used in per share calculations:
Basic (in shares)	259,637	256,154	260,013	255,941
Diluted (in shares)	263,403	259,822	263,746	260,015
Product revenues, net
Revenues:
Revenues	$ 1,524,485	$ 940,380	$ 3,039,592	$ 1,797,633
Collaborative and royalty revenues
Revenues:
Revenues	$ 0	$ 913	$ 0	$ 2,095