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Intangible Assets and Goodwill (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2018
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Sep. 30, 2017
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Oct. 10, 2019
Indefinite-Lived Intangible Assets [Line Items]                    
Intangible asset $ 0 $ 0         $ 400,000,000.0 $ 0    
Intangible asset impairment charges   29,000,000 $ 0 $ 0 $ 0   0 29,000,000 $ 255,340,000  
Goodwill 50,384,000 $ 50,384,000         1,002,158,000 50,384,000    
Semma Therapeutics, Inc.                    
Indefinite-Lived Intangible Assets [Line Items]                    
Intangible asset             387,000,000.0     $ 387,000,000
Goodwill             554,600,000     $ 554,633,000
Exonics Therapeutics                    
Indefinite-Lived Intangible Assets [Line Items]                    
Intangible asset             13,000,000.0      
Goodwill             $ 397,100,000      
Other Intangible Assets | Variable Interest Entity, Primary Beneficiary | BioAxone Biosciences, Inc                    
Indefinite-Lived Intangible Assets [Line Items]                    
Intangible asset impairment charges $ 29,000,000.0             $ 29,000,000.0 29,000,000  
Other Intangible Assets | Variable Interest Entity, Primary Beneficiary | Parion Sciences, Inc                    
Indefinite-Lived Intangible Assets [Line Items]                    
Intangible asset impairment charges           $ 255,300,000     $ 255,300,000