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Marketable Securities and Equity Investments - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Summary of cash, cash equivalents and marketable securities      
Cash $ 2,300,000,000 $ 1,400,000,000  
Other-than-temporary declines in fair value of available-for-sale debt securities 0 0 $ 0
Gross realized gains or losses 0 0 $ 0
Unrealized gains to other (expense) income, net 132,500,000 2,600,000  
CRISPR Therapeutics      
Summary of cash, cash equivalents and marketable securities      
Marketable securities, fair value, investment in common stock 282,100,000 $ 167,300,000  
Realized investment gains (losses) 65,100,000    
Other assets      
Summary of cash, cash equivalents and marketable securities      
Equity securities without readily determinable fair value, amount $ 40,800,000