Stock-based Compensation Expense - (Details) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Stock-based compensation expense:
Stock-based compensation expense	$ 360,489,000	$ 325,047,000	$ 293,236,000
Income tax effect	(124,225,000)	0	0
Total stock-based compensation included in costs and expenses, net of tax	236,264,000	325,047,000	293,236,000
Stock-based compensation expense related to inventories	(1,720,000)	(585,000)	(2,406,000)
Allocated stock-based compensation expense	360,489,000	$ 325,047,000	$ 293,236,000
Stock Options
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends	$ 0.00
Employee stock purchase plan
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	33.43%	36.51%	39.09%
Risk-free interest rate (percent)	2.08%	2.36%	1.24%
Expected term of options (in years)	22 days	22 days	22 days
Expected annual dividends	$ 0	$ 0	$ 0
Weighted average fair value (usd per share)	$ 47.79	$ 44.04	$ 35.90
Restricted stock and restricted stock units (including PSUs)
Stock-based compensation expense:
Stock-based compensation expense	$ 254,276,000	$ 207,845,000	$ 181,258,000
Type of award:
Unrecognized Expense	$ 374,185,000
Weighted-average Recognition Period	2 years 18 days
Stock options
Stock-based compensation expense:
Stock-based compensation expense	$ 96,737,000	$ 107,854,000	$ 105,367,000
Type of award:
Unrecognized Expense	$ 130,153,000
Weighted-average Recognition Period	2 years 6 months
Weighted-average grant-date fair value, granted (usd per share)	$ 61.32	$ 60.83	$ 43.27
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	36.99%	40.50%	45.31%
Risk-free interest rate (percent)	2.32%	2.61%	1.94%
Expected term of options (in years)	4 years 3 months 7 days	4 years 6 months 18 days	4 years 8 months 4 days
Expected annual dividends	$ 0	$ 0	$ 0
ESPP share issuances
Stock-based compensation expense:
Stock-based compensation expense	11,196,000	9,933,000	9,017,000
Type of award:
Unrecognized Expense	$ 4,724,000
Weighted-average Recognition Period	16 days
Performance-based RSUs
Weighted-average assumptions for options and ESPP subscriptions granted
Potential awards, percent of target shares, minimum	0.00%
Potential awards, percent of target shares, maximum	200.00%
Weighted average fair value (usd per share)	$ 183.48
Performance-based RSUs | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Performance-based RSUs | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Financial performance shares | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting rights percentage	33.33%
Financial performance shares | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting rights percentage	33.33%
Financial performance shares | Tranche three
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting rights percentage	33.33%
Non-financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Cost of sales
Stock-based compensation expense:
Stock-based compensation expense	$ 5,575,000	4,543,000	2,500,000
Research and development expenses
Stock-based compensation expense:
Stock-based compensation expense	224,558,000	203,112,000	181,900,000
Sales, general and administrative expenses
Stock-based compensation expense:
Stock-based compensation expense	$ 130,356,000	$ 117,392,000	$ 108,836,000