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Collaborative Arrangements and Acquisitions - Exonics Therapeutics (Details) - USD ($) $ in Thousands		9 Months Ended
	Jul. 16, 2019	Sep. 30, 2019	Dec. 31, 2018
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Fair value of contingent development and regulatory payments		$ 172,041
Goodwill		$ 447,525	$ 50,384
Exonics Therapeutics
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront payment (adjusted for customary working capital adjustments)	$ 266,315
Fair value of contingent development and regulatory payments	172,041
Total purchase price	438,356
Cash and cash equivalents	19,535
Goodwill	397,141
Intangible asset	13,000
Net other assets (liabilities)	8,680
Goodwill, and liabilities assumed, net	$ 438,356