Revenue Recognition (Tables)

9 Months Ended

Sep. 30, 2019

Revenue from Contract with Customer [Abstract]

Schedule of disaggregation of revenue

Total revenues from external customers and collaborators by geographic region consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2019		2018		2019		2018
	(in thousands)
United States	$	710,323	$	620,485	$	2,052,044	$	1,687,963
Outside of the United States
Europe	184,845		132,876		532,809		400,685
Other	54,660		31,174		164,703		88,843
Total revenues outside of the United States	239,505		164,050		697,512		489,528
Total revenues	$	949,828	$	784,535	$	2,749,556	$	2,177,491

Product revenues, net consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2019		2018		2019		2018
	(in thousands)
SYMDEKO/SYMKEVI	$	403,714	$	254,919	$	1,085,821	$	474,601
ORKAMBI	296,711		281,859		906,159		947,186
KALYDECO	249,403		245,733		755,481		748,365
Total product revenues, net	$	949,828	$	782,511	$	2,747,461	$	2,170,152