Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Revenues:
Revenues	$ 949,828	$ 784,535	$ 2,749,556	$ 2,177,491
Costs and expenses:
Cost of sales	131,914	111,255	362,746	287,250
Research and development expenses	555,948	330,510	1,274,529	978,595
Sales, general and administrative expenses	159,674	137,295	463,221	404,406
Change in fair value of contingent consideration	2,959	0	2,959	0
Restructuring income	0	(174)	0	(188)
Total costs and expenses	850,495	578,886	2,103,455	1,670,063
Income from operations	99,333	205,649	646,101	507,428
Interest income	17,628	10,543	51,319	24,381
Interest expense	(14,548)	(18,686)	(44,253)	(53,727)
Other (expense) income, net	(31,747)	(60,995)	64,802	89,662
Income before provision for income taxes	70,666	136,511	717,969	567,744
Provision for income taxes	13,148	8,055	124,393	5,737
Net income	57,518	128,456	593,576	562,007
Loss (income) attributable to noncontrolling interest	0	290	0	(15,638)
Net income attributable to Vertex	$ 57,518	$ 128,746	$ 593,576	$ 546,369
Net income:
Basic (in dollars per share)	$ 0.22	$ 0.51	$ 2.32	$ 2.15
Diluted (in dollars per share)	$ 0.22	$ 0.50	$ 2.28	$ 2.11
Shares used in per share calculations:
Basic (in shares)	256,946	254,905	256,289	254,096
Diluted (in shares)	260,473	259,788	260,182	258,972
Product revenues, net
Revenues:
Revenues	$ 949,828	$ 782,511	$ 2,747,461	$ 2,170,152
Collaborative and royalty revenues
Revenues:
Revenues	$ 0	$ 2,024	$ 2,095	$ 7,339