Revenue Recognition (Tables)

6 Months Ended

Jun. 30, 2019

Revenue from Contract with Customer [Abstract]

Schedule of disaggregation of revenue

Total revenues from external customers and collaborators by geographic region consisted of the following:

	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
	(in thousands)
United States	$	700,618	$	584,811	$	1,341,721	$	1,067,478
Outside of the United States
Europe	180,196		135,914		347,947		267,809
Other	60,479		31,432		110,060		57,669
Total revenues outside of the United States	240,675		167,346		458,007		325,478
Total revenues	$	941,293	$	752,157	$	1,799,728	$	1,392,956

Product revenues, net consisted of the following:

	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
	(in thousands)
SYMDEKO/SYMKEVI	$	361,832	$	185,558	$	682,107	$	219,682
ORKAMBI	316,441		311,261		609,448		665,327
KALYDECO	262,107		253,093		506,078		502,632
Total product revenues, net	$	940,380	$	749,912	$	1,797,633	$	1,387,641