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Nature of Business and Accounting Policies Nature of Business and Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2018
Accounting Policies [Abstract]  
Schedule of New Accounting Pronouncements and Changes in Accounting Principles
The cumulative effect of applying ASC 606 to the Company’s contracts with customers that were not completed as of January 1, 2018 was as follows:
 
Balance as of
 
 
 
Balance as of
 
December 31, 2017
 
Adjustments
 
January 1, 2018
Assets
(in thousands)
Accounts receivable, net
$
281,343

 
$
29,881

 
$
311,224

Inventories
111,830

 
(90
)
 
111,740

Prepaid expenses and other current assets
167,124

 
(17,166
)
 
149,958

Total assets
$
3,546,014

 
$
12,625

 
$
3,558,639

Liabilities and Shareholders’ Equity
 
 
 
 
 
Accrued expenses
$
443,961

 
$
8,586

 
$
452,547

Early access sales accrual
232,401

 
(7,273
)
 
225,128

Other liabilities, current portion
34,373

 
2,083

 
36,456

Accumulated other comprehensive income (loss)
(11,572
)
 
949

 
(10,623
)
Accumulated deficit
(5,119,723
)
 
8,280

 
(5,111,443
)
Total liabilities and shareholders’ equity
$
3,546,014

 
$
12,625

 
$
3,558,639

The impact of adoption on the Company’s consolidated balance sheet as of December 31, 2018 was as follows:
 
As of December 31, 2018
 
As Reported
under ASC 606
 
Balances
without Adoption of ASC 606
 
Effect of Change
Higher/(Lower)
Assets
(in thousands)
Accounts receivable, net
$
409,688

 
$
376,949

 
$
32,739

Inventories
124,360

 
124,506

 
(146
)
Prepaid expenses and other current assets
140,819

 
167,522

 
(26,703
)
Total assets
$
6,245,898

 
$
6,240,008

 
$
5,890

Liabilities and Shareholders’ Equity
 
 
 
 
 
Accrued expenses
$
604,495

 
$
618,873

 
$
(14,378
)
Early access sales accrual
354,404

 
380,609

 
(26,205
)
Other liabilities, current portion
40,589

 
14,355

 
26,234

Accumulated other comprehensive income (loss)
659

 
927

 
(268
)
Accumulated deficit
(2,989,478
)
 
(3,009,985
)
 
20,507

Total liabilities and shareholders’ equity
$
6,245,898

 
$
6,240,008

 
$
5,890

The impact of adoption on the Company’s consolidated statement of operations for the year ended December 31, 2018 was as follows:
 
Year Ended December 31, 2018
 
As Reported
under ASC 606
 
Balances
without Adoption of ASC 606
 
Effect of Change
Higher/(Lower)
 
(in thousands)
Product revenues, net
$
3,038,325

 
$
3,019,484

 
$
18,841

Cost of sales
409,539

 
402,925

 
6,614

Income from operations
635,150

 
622,923

 
12,227

Net income attributable to Vertex
$
2,096,896

 
$
2,084,669

 
$
12,227

 
 
 
 
 
 
Amounts per share attributable to Vertex common shareholders:
 
 
 
 
 
Net income:
 
 
 
 
 
Basic
$
8.24

 
$
8.20

 
$
0.04

Diluted
$
8.09

 
$
8.04

 
$
0.05

Schedule of Cash and Cash Equivalents
The cash, cash equivalents and restricted cash balances for the years ended December 31, 2018 through 2015, which are presented in the Company’s consolidated statements of cash flows subsequent to the adoption of ASU 2016-18, consisted of the following:
 
As of December 31,
 
2018
 
2017
 
2016
 
2015
 
(in thousands)
Cash and cash equivalents
$
2,650,134

 
$
1,665,412

 
$
1,183,945

 
$
714,768

Prepaid expenses and other current assets
4,910

 
2,114

 
47,762

 
78,910

Other assets
3,209

 

 

 
22,083

Cash, cash equivalents and restricted cash per statement of cash flows
$
2,658,253

 
$
1,667,526

 
$
1,231,707

 
$
815,761