Stock-based Compensation Expense and Share Repurchase - (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Stock-based compensation expense:
Stock-based compensation expense related to inventories	$ (80)	$ (972)	$ (545)	$ (1,323)
Total stock-based compensation included in costs and expenses	82,436	73,095	160,572	142,534
Cost of sales
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	1,191	513	2,004	970
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	51,612	43,832	100,100	88,669
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	29,633	28,750	58,468	52,895
Stock options
Stock-based compensation expense:
Share-based compensation expense by type of award	28,591	27,915	54,646	54,896
Type of award:
Unrecognized Expense	169,237		$ 169,237
Weighted-average Recognition Period			2 years 7 months 24 days
Restricted stock and restricted stock units (including PSUs)
Stock-based compensation expense:
Share-based compensation expense by type of award	51,497	43,906	$ 101,915	84,651
Type of award:
Unrecognized Expense	343,132		$ 343,132
Weighted-average Recognition Period			2 years 6 months 26 days
ESPP share issuances
Stock-based compensation expense:
Share-based compensation expense by type of award	2,428	$ 2,246	$ 4,556	$ 4,310
Type of award:
Unrecognized Expense	$ 5,777		$ 5,777
Weighted-average Recognition Period			7 months 17 days