Restructuring Expenses

12 Months Ended

Dec. 31, 2017

Restructuring and Related Activities [Abstract]

Restructuring Expenses

Restructuring Expenses

The Company has adopted several plans to restructure its facilities and operations for which it has incurred restructuring expenses in the three years ended December 31, 2017. The most significant restructuring event during the three years ended December 31, 2017 commenced in February 2017 upon the Company’s decision to consolidate its research activities into its Boston, Milton Park and San Diego locations. The Company closed its research site in Canada as a result of this decision affecting approximately 70 positions. As of December 31, 2017, the restructuring liability associated with this restructuring event relates to the lease for the research site in Canada that terminates in October 2018. The Company does not anticipate any significant additional charges related to this restructuring event in the future. The restructuring charge and other activities related to this restructuring event recorded during the year ended December 31, 2017 were as follows:

	2017
	(in thousands)
Liability, beginning of the period	$	—
Restructuring expense	12,503
Cash payments	(8,602		)
Asset impairments and other non-cash items	(1,812		)
Liability, end of the period	$	2,089