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Collaborative Arrangements and Acquisitions - Janssen Pharmaceuticals, Inc. (Details) - Janssen Pharmaceuticals, Inc. - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jun. 30, 2014
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Collaborative arrangement, up-front payment           $ 35,000,000
Time period of notice required to terminate 6 months          
Reimbursement for development and commercialization of compounds   $ 0 $ 2,800,000 $ 1,800,000 $ 10,600,000