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Collaborative Arrangements and Pending Acquisition - Janssen Pharmaceuticals, Inc. (Details) - Janssen - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Up-front payment     $ 35.0
Time period of notice required to terminate 6 months    
Reimbursement for development and commercialization of compounds $ 0.9 $ 3.5