Product Revenues, Net (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2017	Dec. 31, 2016
Valuation and Qualifying Accounts Disclosure [Line Items]
Customer deposits	$ 104,774	$ 73,416
Product Revenue Allowance and Reserve [Roll Forward]
Balance at December 31, 2016	89,201
Provision related to current period sales	40,668
Adjustments related to prior period sales	(2,617)
Credits/payments made	(38,168)
Balance at March 31, 2017	89,084
Trade Allowances
Product Revenue Allowance and Reserve [Roll Forward]
Balance at December 31, 2016	2,568
Provision related to current period sales	5,638
Adjustments related to prior period sales	(169)
Credits/payments made	(5,654)
Balance at March 31, 2017	2,383
Rebates, Chargebacks and Discounts
Product Revenue Allowance and Reserve [Roll Forward]
Balance at December 31, 2016	81,927
Provision related to current period sales	28,567
Adjustments related to prior period sales	(2,344)
Credits/payments made	(27,916)
Balance at March 31, 2017	80,234
Product Returns
Product Revenue Allowance and Reserve [Roll Forward]
Balance at December 31, 2016	3,492
Provision related to current period sales	370
Adjustments related to prior period sales	(48)
Credits/payments made	(170)
Balance at March 31, 2017	3,644
Other Incentives
Product Revenue Allowance and Reserve [Roll Forward]
Balance at December 31, 2016	1,214
Provision related to current period sales	6,093
Adjustments related to prior period sales	(56)
Credits/payments made	(4,428)
Balance at March 31, 2017	2,823
Cystic Fibrosis Foundation Therapeutics Incorporated
Valuation and Qualifying Accounts Disclosure [Line Items]
Customer deposits	$ 104,800

The current portion of money or property received from customers which is either to be returned upon satisfactory contract completion or applied to customer receivables in accordance with the terms of the contract or the understandings.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.20)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 4
-Subparagraph (SX 210.12-09)
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e24092-122690

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