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Inventories
3 Months Ended
Mar. 31, 2017
Inventory Disclosure [Abstract]  
Inventories
Inventories
Inventories consisted of the following:
 
As of March 31, 2017
 
As of December 31, 2016
 
(in thousands)
Raw materials
$
9,172

 
$
6,348

Work-in-process
60,921

 
56,672

Finished goods
11,927

 
14,584

Total
$
82,020

 
$
77,604


Based on its evaluation of, among other factors, information regarding tezacaftor's safety and efficacy, the Company has begun capitalizing insignificant inventory costs for tezacaftor manufactured in preparation for its potential product launch. In periods prior, the Company expensed costs associated with tezacaftor’s raw materials and work-in-process as a development expense. The Company is planning to submit a New Drug Application to the United States Food and Drug Administration and a Marketing Authorization Application to the European Medicines Agency for tezacaftor in combination with ivacaftor during the third quarter of 2017. The Company plans to continue to monitor the status of the tezacaftor regulatory process and the other factors used to determine whether or not to capitalize the tezacaftor inventory and, if there are significant negative developments regarding tezacaftor, the Company could be required to impair previously capitalized costs.