Collaborative Arrangements Collaborative Arrangements - Janssen Pharmaceuticals, Inc. (Details) - Janssen - USD ($) $ in Millions	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015	Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Up-front payment					$ 35.0
Reimbursement for development and commercialization of compounds	$ 4.3	$ 7.1	$ 7.8	$ 14.7
Time period of notice required to terminate			6 months