Condensed Consolidated Balance Sheets (unaudited) - USD ($) $ in Thousands	Jun. 30, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 605,866	$ 714,768
Marketable securities, available for sale	465,570	327,694
Restricted cash and cash equivalents (VIE)	70,513	78,910
Accounts receivable, net	189,356	177,639
Inventories	66,589	57,207
Prepaid expenses and other current assets	56,256	50,935
Total current assets	1,454,150	1,407,153
Property and equipment, net	690,607	697,715
Intangible assets	284,340	284,340
Goodwill	50,384	50,384
Cost method investment in CRISPR	33,213	0
Notes receivable	0	30,000
Restricted cash	22,085	22,083
Other assets	14,203	6,912
Total assets	2,548,982	2,498,587
Current liabilities:
Accounts payable	51,302	74,942
Accrued expenses	275,165	305,820
Deferred revenues, current portion	11,468	16,296
Accrued restructuring expenses, current portion	7,683	7,894
Capital lease obligations, current portion	17,446	15,545
Senior secured term loan, current portion	221,576	71,296
Other liabilities, current portion	38,215	14,374
Total current liabilities	622,855	506,167
Deferred revenues, excluding current portion	7,411	9,714
Accrued restructuring expenses, excluding current portion	4,801	7,464
Capital lease obligations, excluding current portion	34,317	42,923
Deferred tax liability	132,810	110,439
Construction financing lease obligation, excluding current portion	472,374	472,611
Senior secured term loan, net of current portion and discount	74,921	223,863
Other liabilities, excluding current portion	30,648	31,778
Total liabilities	1,380,137	1,404,959
Commitments and contingencies
Shareholders’ equity:
Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued and outstanding at June 30, 2016 and December 31, 2015	0	0
Common stock, $0.01 par value; 500,000,000 and 500,000,000 shares authorized at June 30, 2016 and December 31, 2015, respectively; 247,703,932 and 246,306,818 shares issued and outstanding at June 30, 2016 and December 31, 2015, respectively	2,440	2,427
Additional paid-in capital	6,350,244	6,197,500
Accumulated other comprehensive (loss) income	(3,390)	1,824
Accumulated deficit	(5,367,940)	(5,261,784)
Total Vertex shareholders' equity	981,354	939,967
Noncontrolling interest	187,491	153,661
Total shareholders’ equity	1,168,845	1,093,628
Total liabilities and shareholders’ equity	$ 2,548,982	$ 2,498,587