Condensed Consolidated Balance Sheets (unaudited) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 604,245	$ 714,768
Marketable securities, available for sale	421,373	327,694
Restricted cash and cash equivalents (VIE)	76,273	78,910
Accounts receivable, net	181,878	177,639
Inventories	63,200	57,207
Prepaid expenses and other current assets	55,866	50,935
Total current assets	1,402,835	1,407,153
Property and equipment, net	690,521	697,715
Intangible assets	284,340	284,340
Goodwill	50,384	50,384
Cost Method Investment in CRISPR	30,138	0
Notes Receivable	0	30,000
Restricted cash	22,088	22,083
Other assets	7,600	6,912
Total assets	2,487,906	2,498,587
Current liabilities:
Accounts payable	75,221	74,942
Accrued expenses	272,665	305,820
Deferred revenues, current portion	14,705	16,296
Accrued restructuring expenses, current portion	7,790	7,894
Capital lease obligations, current portion	17,292	15,545
Senior secured term loan, current portion	146,251	71,296
Other liabilities, current portion	18,117	14,374
Total current liabilities	552,041	506,167
Deferred revenues, excluding current portion	8,490	9,714
Accrued restructuring expenses, excluding current portion	6,145	7,464
Capital lease obligations, excluding current portion	38,886	42,923
Deferred tax liability	112,259	110,439
Construction financing lease obligation, excluding current portion	472,494	472,611
Senior secured term loan, net of current portion and discount	149,571	223,863
Other liabilities, excluding current portion	31,822	31,778
Total liabilities	$ 1,371,708	$ 1,404,959
Commitments and contingencies
Shareholders’ equity:
Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued and outstanding at March 31, 2016 and December 31, 2015	$ 0	$ 0
Common stock, $0.01 par value; 500,000,000 and 500,000,000 shares authorized at March 31, 2016 and December 31, 2015, respectively; 247,286,705 and 246,306,818 shares issued and outstanding at March 31, 2016 and December 31, 2015, respectively	2,429	2,427
Additional paid-in capital	6,262,964	6,197,500
Accumulated other comprehensive (loss) income	(4,899)	1,824
Accumulated deficit	(5,303,415)	(5,261,784)
Total Vertex shareholders' equity	957,079	939,967
Noncontrolling interest	159,119	153,661
Total shareholders’ equity	1,116,198	1,093,628
Total liabilities and shareholders’ equity	$ 2,487,906	$ 2,498,587