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Stock-based Compensation Expense (Details) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Stock-based compensation expense:      
Stock-based compensation expense $ 231,025,000 $ 177,542,000 $ 126,835,000
Less: stock-based compensation expense capitalized to inventories (4,087,000) (1,423,000) (1,048,000)
Allocated stock-based compensation expense 231,025,000 $ 177,542,000 $ 126,835,000
Stock Options      
Weighted-average assumptions for options and ESPP subscriptions granted      
Expected annual dividends $ 0    
Employee Stock Purchase Plan      
Weighted-average assumptions for options and ESPP subscriptions granted      
Weighted average fair value (usd per share) $ 37.84 $ 29.59 $ 21.08
Expected stock price volatility (percent) 47.20% 60.32% 54.69%
Risk-free interest rate (percent) 0.40% 0.09% 0.08%
Expected term of options (in years) 8 months 20 days 9 months 8 months 26 days
Expected annual dividends $ 0 $ 0 $ 0
Stock options      
Stock-based compensation expense:      
Stock-based compensation expense 129,276,000 $ 99,961,000 $ 84,599,000
Type of award:      
Unrecognized Expense Net of Estimated Forfeitures $ 170,971,000    
Weighted-average Recognition Period (in years) 2 years 2 months 1 day    
Weighted-average grant-date fair value, granted (in dollars per share) $ 52.16 $ 39.95 $ 25.79
Weighted-average assumptions for options and ESPP subscriptions granted      
Expected stock price volatility (percent) 47.29% 50.86% 46.20%
Risk-free interest rate (percent) 1.61% 1.77% 1.25%
Expected term of options (in years) 5 years 3 months 11 days 5 years 5 months 19 days 5 years 9 months 22 days
Expected annual dividends $ 0 $ 0 $ 0
Restricted stock and restricted stock units      
Stock-based compensation expense:      
Stock-based compensation expense 98,811,000 70,678,000 36,479,000
Type of award:      
Unrecognized Expense Net of Estimated Forfeitures $ 168,742,000    
Weighted-average Recognition Period (in years) 2 years 7 months 2 days    
ESPP share issuances      
Stock-based compensation expense:      
Stock-based compensation expense $ 7,025,000 8,326,000 6,805,000
Type of award:      
Unrecognized Expense Net of Estimated Forfeitures $ 6,232,000    
Weighted-average Recognition Period (in years) 7 months 24 days    
Research and development expenses      
Stock-based compensation expense:      
Stock-based compensation expense $ 152,955,000 116,998,000 81,183,000
Sales, general and administrative expenses      
Stock-based compensation expense:      
Stock-based compensation expense $ 78,070,000 $ 60,544,000 $ 45,652,000