Collaborative Arrangements - BioAxone Biosciences, Inc. (Details) - BioAxone Biosciences, Inc - USD ($)	1 Months Ended	3 Months Ended
	Oct. 31, 2014	Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Up-front payment		$ 10,000,000
Maximum license fees and milestone payments	$ 90,000,000.0
In-process research and development intangible assets		29,000,000
Deferred tax liability attributable to BioAxone		$ 11,300,000
Purchase option, term of extension of expiration date	1 year