Segment Information

12 Months Ended

Dec. 31, 2015

Segment Reporting [Abstract]

Segment Information

Segment Information

Segment reporting is prepared on the same basis that the Company’s chief executive officer, who is the Company’s chief operating decision maker, manages the business, makes operating decisions and assesses performance. The Company operates in one segment, pharmaceuticals. Enterprise-wide disclosures about revenues, significant customers, and property and equipment, net by location are presented below.

Revenues by Product

Product revenues, net consisted of the following:

	2015		2014		2013
	(in thousands)
KALYDECO	$	631,674	$	463,750	$	371,285
ORKAMBI	350,663		—		—
INCIVEK	17,987		24,071		466,360
Total product revenues, net	$	1,000,324	$	487,821	$	837,645

Revenues by Geographic Location

Total revenues from external customers and collaborators by geographic region consisted of the following. Product revenues are attributed to countries based on the location of the customer. Collaborative revenues are attributed to the operations of the Company in the United States. Royalty revenues are attributed to countries based on the location of the collaborator.

	2015		2014		2013
	(in thousands)
United States	$	763,316	$	361,074	$	896,952
Outside of the United States
Europe	219,596		197,611		279,557
Other	49,424		21,730		35,466
Total revenues outside of the United States	269,020		219,341		315,023
Total revenues	$	1,032,336	$	580,415	$	1,211,975

In 2015 and 2014, revenues attributable to the United Kingdom were the majority of the Company’s European revenues.

Significant Customers

Gross revenues and accounts receivable from each of the Company’s customers who individually accounted for 10% or more of total gross revenues and/or 10% or more of total gross accounts receivable consisted of the following:

	Percent of Total Gross Revenues						Percent of Gross Accounts Receivable
	Year Ended December 31,						As of December 31,
	2015		2014		2013		2015		2014
Walgreen Co.	20	%	12	%	<10	%	15	%	11	%
CVS/Caremark	17	%	<10	%	<10	%	17	%	<10	%
Accredo/Curascript	15	%	<10	%	<10	%	16	%	<10	%
Bupa Home Healthcare Limited	<10	%	<10	%	<10	%	<10	%	20	%
Janssen Inc.	<10	%	<10	%	N/A		<10	%	12	%
Janssen NV	<10	%	<10	%	22	%	<10	%	<10	%
AmerisourceBergen Drug Corporation	<10	%	<10	%	21	%	<10	%	<10	%
McKesson Corporation	<10	%	<10	%	21	%	<10	%	<10	%

Property and Equipment, Net by Location

Property and equipment, net by location consisted of the following:

	As of December 31,
	2015		2014
	(in thousands)
United States	$	661,421	$	676,968
Outside of the United States
United Kingdom	32,793		33,628
Other	3,501		5,216
Total property and equipment, net outside of the United States	36,294		38,844
Total property and equipment, net	$	697,715	$	715,812