Stock-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2015	Jun. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Stock-based compensation expense:
Less stock-based compensation expense capitalized to inventories	$ (1,281)		$ (456)	$ (3,318)	$ (905)
Total stock-based compensation included in costs and expenses	65,734		46,136	186,379	135,160
Stock options
Stock-based compensation expense:
Stock-based compensation expense by type of award:	39,074		26,291	105,720	78,403
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	197,031			$ 197,031
Weighted-average recognition period (in years)				2 years 3 months 18 days
Restricted stock and restricted stock units
Stock-based compensation expense:
Stock-based compensation expense by type of award:	26,203		18,418	$ 78,274	51,431
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	190,786			$ 190,786
Weighted-average recognition period (in years)				2 years 8 months 23 days
ESPP share issuances
Stock-based compensation expense:
Stock-based compensation expense by type of award:	1,738		1,883	$ 5,703	6,231
Type of award:
Unrecognized Expense, Net of Estimated Forfeitures	1,885			$ 1,885
Weighted-average recognition period (in years)				5 months 9 days
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	44,701		31,131	$ 124,550	91,284
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	$ 21,033		$ 15,005	$ 61,829	$ 43,876
Stock and Option Plan 2013 [Member]
Type of award:
Number of additional shares authorized		7,800,000