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Collaborative Arrangements (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Jun. 04, 2015
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
Recognized Collaborative Revenue [Abstract]            
Royalty revenues   $ 5,759 $ 8,386 $ 17,628 $ 32,134  
Collaborative revenues   1,546 33,502 2,999 40,846  
Total revenues   309,816 178,987 614,401 435,859  
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Restricted cash and cash equivalents (VIE)   75,765   75,765   $ 8,418
Prepaid expenses and other current assets   63,388   63,388   44,175
Intangible assets   284,340   284,340   29,000
Goodwill   50,384   50,384   39,915
Deferred tax liability   (113,860)   (113,860)   (15,044)
Other assets   11,061   11,061   3,265
Accounts payable   78,899   78,899   71,194
Accrued expenses   249,698   249,698   209,676
Other liabilities, excluding current portion   34,990   34,990   21,707
Noncontrolling interest   154,585   154,585   21,177
Loss attributable to noncontrolling interest before provision for income taxes   (92,486) (166,577) (481,752) (556,281)  
Provision for income taxes   (1,330) (3,419) (31,760) (4,915)  
Net (income) loss attributable to noncontrolling interest   1,333 0 (30,909) 0  
Janssen            
Recognized Collaborative Revenue [Abstract]            
Royalty revenues   158 2,284 1,742 12,917  
Collaborative revenues   441 1,390 1,620 4,262  
Total revenues   599 $ 3,674 3,362 $ 17,179  
Up-front payment           35,000
Parion Sciences, Inc            
Recognized Collaborative Revenue [Abstract]            
Up-front payment $ 80,000          
Fair value of contingent milestone and royalty payments 175,340          
Business combination, consideration transferred 255,340          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Intangible assets 255,340          
Goodwill 10,468          
Deferred tax liability (91,023)          
Net other assets (liabilities) (10,468)          
Net assets attributable to noncontrolling interests $ 164,317          
Provision for income taxes   (800)   (30,400)    
Increase in fair value of contingent milestone and royalty payments   (4,500)   (2,900)    
Variable Interest Entity, Primary Beneficiary            
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net [Abstract]            
Restricted cash and cash equivalents (VIE)   75,765   75,765   8,418
Prepaid expenses and other current assets   3,057   3,057   268
Intangible assets   284,340   284,340   29,000
Goodwill   19,391   19,391   8,923
Deferred tax liability   (110,360)   (110,360)   (11,544)
Other assets   461   461   42
Accounts payable   1,115   1,115   189
Accrued expenses   32,519   32,519   3,891
Other liabilities, excluding current portion   300   300   300
Noncontrolling interest   154,585   154,585   $ 21,177
Loss attributable to noncontrolling interest before provision for income taxes   (1,743)   (3,322)    
Provision for income taxes   (777)   (30,367)    
Increase in fair value of contingent milestone and royalty payments   (3,853)   (2,780)    
Net (income) loss attributable to noncontrolling interest   $ 1,333   $ 30,909