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Employee Benefits (Details) (USD $)
Share data in Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Compensation and Retirement Disclosure [Abstract]      
Maximum percentage of annual compensation contributed by the participant (percent) 60.00%vrtx_MaximumDefinedContributionPlanEmployeeContributionPercentageOfCompensation    
Accrued employee benefits $ 12,000,000us-gaap_AccruedEmployeeBenefitsCurrent $ 12,600,000us-gaap_AccruedEmployeeBenefitsCurrent $ 12,000,000us-gaap_AccruedEmployeeBenefitsCurrent
Common stock shares remained available for grant (shares) 755vrtx_DefinedContributionPlanNumberOfSharesAvailableForGrant    
Matching contributions to the Vertex 401(k) Plan:      
Discretionary matching contributions during the year ended December 31,   $ 5,930,000us-gaap_DefinedContributionPlanCostRecognized $ 10,261,000us-gaap_DefinedContributionPlanCostRecognized
Shares issued during the year ended December 31   99us-gaap_StockIssuedDuringPeriodSharesEmployeeBenefitPlan 242us-gaap_StockIssuedDuringPeriodSharesEmployeeBenefitPlan
Shares issuable as of the year ended December 31   0vrtx_StockIssuableAtPeriodEndUnder401KRetirementPlan 53vrtx_StockIssuableAtPeriodEndUnder401KRetirementPlan