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Long Term Obligations Fan Pier Leases (Details) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
leases
building
sqft
Property, Plant and Equipment [Line Items]        
Number of leases       2vrtx_LeaseAgreementNumberOfLeases
Area of real estate property (in square feet)       1,100,000us-gaap_AreaOfRealEstateProperty
Lease Agreements Number of Buildings       2vrtx_LeaseAgreementsNumberOfBuildings
Optional term of lease agreement (in years)       10 years
Depreciation expense $ 62,300,000us-gaap_Depreciation $ 47,300,000us-gaap_Depreciation $ 35,700,000us-gaap_Depreciation  
Rental expense 38,900,000us-gaap_LeaseAndRentalExpense 57,700,000us-gaap_LeaseAndRentalExpense 57,100,000us-gaap_LeaseAndRentalExpense  
Property and equipment, net 715,812,000us-gaap_PropertyPlantAndEquipmentNet 696,911,000us-gaap_PropertyPlantAndEquipmentNet    
Construction financing lease obligation, current and noncurrent 473,400,000vrtx_Constructionfinancingleaseobligationcurrentandnoncurrent 440,900,000vrtx_Constructionfinancingleaseobligationcurrentandnoncurrent    
Buildings        
Property, Plant and Equipment [Line Items]        
Interest expense 60,200,000us-gaap_InterestExpense
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_BuildingMember
     
Depreciation expense 13,400,000us-gaap_Depreciation
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_BuildingMember
     
Rental expense 6,500,000us-gaap_LeaseAndRentalExpense
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_BuildingMember
     
Construction-in-process        
Property, Plant and Equipment [Line Items]        
Property and equipment, net $ 515,000,000us-gaap_PropertyPlantAndEquipmentNet
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ConstructionInProgressMember
$ 503,400,000us-gaap_PropertyPlantAndEquipmentNet
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_ConstructionInProgressMember