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Marketable Securities (Details) (USD $)
Dec. 31, 2014
Dec. 31, 2013
Summary of cash, cash equivalents and marketable securities    
Amortized Cost $ 1,387,229,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost $ 1,465,034,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
Gross Unrealized Gains 88,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain 136,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
Gross Unrealized Losses (211,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross (94,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
Fair Value 1,387,106,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue 1,465,076,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
Total cash and cash equivalents    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 625,259,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
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569,299,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
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= us-gaap_CashAndCashEquivalentsMember
Gross Unrealized Gains 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
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0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
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Gross Unrealized Losses 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
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0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
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Fair Value 625,259,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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= us-gaap_CashAndCashEquivalentsMember
569,299,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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= us-gaap_CashAndCashEquivalentsMember
Cash and money market funds    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 625,259,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
569,299,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
Gross Unrealized Gains 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
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= vrtx_CashAndMoneyMarketFundsMember
Gross Unrealized Losses 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
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= vrtx_CashAndMoneyMarketFundsMember
0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
Fair Value 625,259,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
569,299,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CashAndMoneyMarketFundsMember
Total marketable securities    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 761,970,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
895,735,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
Gross Unrealized Gains 88,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
136,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
Gross Unrealized Losses (211,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
(94,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
Fair Value 761,847,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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= us-gaap_AvailableforsaleSecuritiesMember
895,777,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_AvailableforsaleSecuritiesMember
Government-sponsored enterprise securities    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 463,788,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
600,496,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
Gross Unrealized Gains 14,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
7,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
Gross Unrealized Losses (52,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
(53,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
Fair Value 463,750,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
600,450,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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= us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember
Commercial paper (due within 1 year)    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 51,674,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_CommercialPaperMember
83,384,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_CommercialPaperMember
Gross Unrealized Gains 72,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= us-gaap_CommercialPaperMember
109,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
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= us-gaap_CommercialPaperMember
Gross Unrealized Losses 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
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= us-gaap_CommercialPaperMember
0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
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= us-gaap_CommercialPaperMember
Fair Value 51,746,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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83,493,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
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= us-gaap_CommercialPaperMember
Corporate debt securities (due within 1 year)    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 196,065,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
189,674,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
Gross Unrealized Gains 2,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
14,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
Gross Unrealized Losses (66,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
(34,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
Fair Value 196,001,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
189,654,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueWithinOneYearMember
Corporate debt securities (due after 1 year through 5 years)    
Summary of cash, cash equivalents and marketable securities    
Amortized Cost 50,443,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
22,181,000vrtx_CashCashEquivalentsAvailableForSaleSecuritiesAmortizedCost
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
Gross Unrealized Gains 0vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
6,000vrtx_CashCashEquivalentsAvailableforsaleSecuritiesGrossUnrealizedGain
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
Gross Unrealized Losses (93,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
(7,000)vrtx_CashCashEquivalentsAvailableforsaleSecuritiesUnrealizedLossGross
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
Fair Value 50,350,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
22,180,000vrtx_CashCashEquivalentsAndAvailableForSaleSecuritiesFairValue
/ vrtx_ScheduleOfCashCashEquivalentsAndAvailableForSaleSecuritiesTypesOfFinancialInstrumentsAxis
= vrtx_CorporateDebtSecuritiesDueAfterOneYearThroughFiveYearsMember
BioAxone Biosciences, Inc | Variable Interest Entity, Primary Beneficiary    
Summary of cash, cash equivalents and marketable securities    
Cash and cash equivalents $ 8,400,000vrtx_VariableInterestEntityConsolidatedCarryingAmountCashandCashEquivalents
/ vrtx_CollaborativeArrangementsByAgreementAxis
= vrtx_BioAxoneBiosciencesIncMember
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