Segment Information

12 Months Ended

Dec. 31, 2014

Segment Reporting [Abstract]

Segment Information

Segment Information

The Company operates in one segment, pharmaceuticals. Enterprise-wide disclosures about revenues, significant customers, and property and equipment, net by location are presented below.

Revenues by Product

Product revenues, net consisted of the following:

	2014		2013		2012
	(in thousands)
KALYDECO	$	463,750	$	371,285	$	171,645
INCIVEK	24,071		466,360		1,161,813
Total product revenues, net	$	487,821	$	837,645	$	1,333,458

Revenues by Geographic Location

Total revenues from external customers and collaborators by geographic region consisted of the following. Product revenues are attributed to countries based on the location of the customer. Collaborative revenues are attributed to the operations of the Company in the United States. Royalty revenues are attributed to countries based on the location of the collaborator.

	2014		2013		2012
	(in thousands)
United States	$	361,074	$	896,952	$	1,373,516
Outside of the United States
Europe	197,611		279,557		129,786
Other	21,730		35,466		23,740
Total revenues outside of the United States	219,341		315,023		153,526
Total revenues	$	580,415	$	1,211,975	$	1,527,042

In 2014, revenues attributable to the United Kingdom were the majority of the Company’s European revenues.

Significant Customers

Gross revenues and accounts receivable from each of the Company’s customers who individually accounted for 10% or more of total gross revenues and/or 10% or more of total gross accounts receivable consisted of the following:

	Percent of Total Gross Revenues						Percent of Gross Accounts Receivable
	Year Ended December 31,						As of December 31,
	2014		2013		2012		2014		2013
Walgreen Co.	12	%	<10	%	<10	%	11	%	<10	%
Bupa Home Healthcare Limited	<10	%	<10	%	N/A		20	%	14	%
Janssen Inc.	<10	%	N/A		N/A		12	%	N/A
Janssen NV	<10	%	22	%	<10	%	<10	%	28	%
AmerisourceBergen Drug Corporation	<10	%	21	%	32	%	<10	%	<10	%
McKesson Corporation	<10	%	21	%	29	%	<10	%	<10	%
Cardinal Health Incorporated	<10	%	<10	%	15	%	<10	%	<10	%

Property and Equipment, Net by Location

Property and equipment, net by location consisted of the following:

	As of December 31,
	2014		2013
	(in thousands)
United States	$	676,968	$	657,587
Outside of the United States
United Kingdom	33,628		29,970
Other	5,216		9,354
Total property and equipment, net outside of the United States	38,844		39,324
Total property and equipment, net	$	715,812	$	696,911