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Income Taxes (Details) (USD $)
3 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Dec. 31, 2013
Tax Carryforwards      
Benefit from income taxes $ 803,000 $ (130,313,000)  
Current state and local tax expense   (130,300,000)  
Intangible asset impairment charge 0 412,900,000  
Deferred federal income tax expense (benefit)   127,600,000  
Unrecognized tax benefits 2,600,000   2,000,000
Federal income tax net operating loss carryfowards     2,700,000,000
Federal income tax credit carryforwards     120,100,000
State income tax net operating loss carryforwards     966,800,000
State income tax credit credit carryforwards     66,900,000
Total Vertex Shareholders' Equity
     
Tax Carryforwards      
Current state and local tax expense   (126,900,000)  
Noncontrolling Interest (Alios)
     
Tax Carryforwards      
Current state and local tax expense   (3,400,000)  
VX-222Asset
     
Tax Carryforwards      
Intangible assets   0  
Intangible asset impairment charge   $ 412,900,000