Segment Information (Tables)

12 Months Ended

Dec. 31, 2012

Segment Reporting [Abstract]

Revenues by Product

Product revenues, net consisted of the following:

	2012		2011		2010
	(in thousands)
INCIVEK	$	1,161,813	$	950,889	$	—
KALYDECO	171,645		—		—
Total product revenues, net	$	1,333,458	$	950,889	$	—

Revenues and Property and Equipment by Location

The following table summarizes total revenues from external customers and collaborators by geographic region. Product revenues are attributed to countries based on the location of the customer. Collaborative revenues are attributed to the operations of the Company in the United States. Royalty revenues are attributed to countries based on the location of the collaborator.

	2012		2011		2010
	(in thousands)
United States	$	1,373,516	$	1,389,568	$	143,370
Outside of the United States
Europe	129,786		20,289		—
Other	23,740		769		—
Total revenues outside of the United States	153,526		21,058		—
Total revenues	$	1,527,042	$	1,410,626	$	143,370

The following table summarizes property and equipment, net by location:

	As of December 31,
	2012		2011
	(in thousands)
United States	$	400,102	$	109,480
Outside of the United States
United Kingdom	30,622		21,377
Other	2,885		2,319
Total property and equipment, net outside of the United States	33,507		23,696
Total property and equipment, net	$	433,609	$	133,176

Significant Customers

The following table summarizes gross revenues and accounts receivable from each of the Company’s customers who individually accounted for 10% or more of total gross revenues and/or 10% or more of total accounts receivable:

	Percent of Total Gross Revenues						Percent of Accounts Receivable
	Year Ended December 31,						As of December 31,
	2012		2011		2010		2012		2011
AmerisourceBergen Drug Corporation	32	%	25	%	—	%	22	%	35	%
McKesson Corporation	29	%	24	%	—	%	26	%	30	%
Cardinal Health Incorporated	15	%	15	%	—	%	<10	%	20	%
Janssen	<10	%	19	%	21	%	26	%	10	%
Mitsubishi Tanabe	<10	%	<10	%	57	%	—	%	<10	%