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Stock-based Compensation Expense (Tables)
12 Months Ended
Dec. 31, 2012
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Stock-based compensation expense by line item
The effect of stock-based compensation expense during the three years ended December 31, 2012 was as follows:
 
2012
2011
2010
 
(in thousands)
Stock-based compensation expense by line item:
 
 
 
Research and development expenses
$
71,533

$
75,574

$
65,198

Sales, general and administrative expenses
42,752

42,652

25,926

Total stock-based compensation expense included in costs and expenses
$
114,285

$
118,226

$
91,124

Stock-based compensation expense by type of award
The stock-based compensation expense by type of award during the three years ended December 31, 2012 was as follows:
 
2012
2011
2010
 
(in thousands)
Stock-based compensation expense by type of award:
 
 
 
Stock options
$
79,047

$
83,098

$
64,005

Restricted stock and restricted stock units
29,194

30,708

22,960

ESPP share issuances
7,298

5,462

4,159

Less stock-based compensation expense capitalized to inventories
(1,254
)
(1,042
)

Total stock-based compensation expense included in costs and expenses
$
114,285

$
118,226

$
91,124

Unrecognized stock-based compensation expense, net of estimated forfeitures
The following table sets forth the Company’s unrecognized stock-based compensation expense, net of estimated forfeitures, as of December 31, 2012 by type of award and the weighted-average period over which that expense is expected to be recognized:
 
As of December 31, 2012
 
Unrecognized Expense
Net of
Estimated Forfeitures
Weighted-average
Recognition
Period
 
(in thousands)
(in years)
Type of award:
 
 
Stock options
$156,225
2.69
Restricted stock and restricted stock units
68,094

2.58
ESPP share issuances
5,661

0.65
Schedule of assumptions used to estimate the grant date fair value of options
The fair value of each option granted during 2012, 2011 and 2010 was estimated on the date of grant using the Black-Scholes option pricing model with the following weighted-average assumptions:
 
2012
2011
2010
Expected stock price volatility
47.93
%
49.53
%
52.17
%
Risk-free interest rate
0.95
%
2.09
%
2.44
%
Expected term of options (in years)
5.78

5.74

5.71

Expected annual dividends



Schedule of assumptions used to estimate the grant date fair value employee stock purchase plan
he following table reflects the weighted-average assumptions used in the Black-Scholes option pricing model for 2012, 2011 and 2010:
 
2012
2011
2010
Expected stock price volatility
46.90
%
51.32
%
43.92
%
Risk-free interest rate
0.16
%
0.08
%
0.24
%
Expected term (in years)
0.74

0.72

0.71

Expected annual dividends