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Other Consolidated Financial Statement Detail (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Other Income (Expense), Net          
Interest income $ 6.0 $ 30.5 $ 38.0 $ 90.8  
Interest expense (56.3) (45.8) (166.5) (141.4)  
Gain (loss) on investments, net (82.1) (4.1) (52.6) 198.9  
Foreign exchange gains (losses), net 3.1 (4.2) (5.4) (4.7)  
Other, net 0.7 (3.7) 0.4 (11.0)  
Total other income (expense), net (128.6) (27.3) (186.1) 132.6  
Equity Securities, FV-NI, Gain (Loss), Alternative [Abstract]          
Net gains (losses) recognized during the period on equity securities (82.3) (4.6) (40.3) 197.3  
Less: Net gains (losses) recognized during the period on equity securities sold during the period 0.0 4.4 0.0 (46.8)  
Unrealized gains (losses) recognized during the period on equity securities (82.3) $ (9.0) (40.3) $ 150.5  
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances 1,271.8   1,271.8   $ 1,198.9
Collaboration expenses 279.0   279.0   309.1
Royalties and licensing fees 222.8   222.8   220.9
Collaboration expenses 277.9   277.9   281.6
Current portion of contingent consideration obligations 164.4   164.4   148.4
Construction in progress 23.4   23.4   78.0
Other 1,274.8   1,274.8   726.7
Total accrued expenses and other 3,286.2   3,286.2   2,765.8
Component of accrued expenses and other          
Accrued Expenses and Other          
Revenue-related reserves for discounts and allowances $ 1,043.9   $ 1,043.9   $ 1,001.1