Investments in Variable Interest Entities (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | |||
---|---|---|---|---|---|
Jun. 30, 2015 |
Jun. 30, 2014 |
Jun. 30, 2015 |
Jun. 30, 2014 |
Dec. 31, 2014 |
|
Investment in Variable Interest Entities (Textual) [Abstract] | |||||
Research and development | $ 490,728 | $ 447,273 | $ 951,277 | $ 976,157 | |
Investment in biotechnology companies that are determined to be unconsolidated variable interest entities | 8,500 | 8,500 | $ 7,900 | ||
Neurimmune | |||||
Investment in Variable Interest Entities (Textual) [Abstract] | |||||
Remaining potential development milestone payments and royalties on commercial sales under the terms of collaboration agreement | 335,000 | ||||
Expected milestone payment for initiation of a late stage clinical trial | 60,000 | ||||
Research and development | $ 35,000 | $ 10,600 | $ 47,800 | $ 21,700 |