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Cumulative amount of payments received under the collaboration agreement as of the end of the reporting period.

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No definition available.

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- Definition

The maximum amount of payments receivable for each additional medicine developed under the collaboration agreement.

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No definition available.

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The maximum amount of payments receivable for development milestones under the collaboration agreement.

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No definition available.

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- Definition

Maximum amount of payments receivable for license fees and milestone payments under the collaboration agreement.

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No definition available.

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- Definition

The maximum amount of payments receivable for regulatory milestones under the collaboration agreement.

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No definition available.

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- Definition

The maximum amount of payments receivable for sales milestones under the collaboration agreement.

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No definition available.

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- Definition

The amount of milestone payments received during the period under the collaboration agreement.

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No definition available.

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The minimum amount of payments receivable for license fees and milestone payments under the collaboration agreement.

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No definition available.

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The next potential payment to be earned under the collaboration agreement.

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No definition available.

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- Definition

Number of disease indications for which studies are currently being conducted under the collaboration agreement.

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No definition available.

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The number of separate performance obligations under the collaboration agreement.

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No definition available.

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The amount of consideration the Company earned or is eligible to earn under the collaboration agreement, including any variable consideration.

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No definition available.

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Royalty percentage received on the net sales of a medicine by a collaboration partner under the collaboration agreement.

+ References

No definition available.

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The amount of upfront payments received during the period under the collaboration agreement.

+ References

No definition available.

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaborative Arrangements and Licensing Agreements, Roche (Details) $ in Thousands	1 Months Ended	3 Months Ended		12 Months Ended
	Apr. 30, 2013 USD ($) PerformanceObligation	Dec. 31, 2020 USD ($)	Dec. 31, 2018 USD ($)	Dec. 31, 2021 USD ($) Indication	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2017 USD ($)	Oct. 31, 2018 USD ($) PerformanceObligation
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				$ 810,456	$ 729,264	$ 1,122,599
R&D Revenue [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				468,061	364,565	$ 770,149
Roche [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Deferred revenue		$ 47,200		$ 31,600	$ 47,200
Roche [Member] \| Revenue [Member] \| Strategic Partner [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Concentration percentage				2.00%	1.00%	5.00%
Roche [Member] \| R&D Revenue [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				$ 17,200	$ 5,900	$ 57,000
Huntington's Disease [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Upfront payment received	$ 30,000
Milestone payment received							$ 3,000
Maximum amount of payments receivable for license fees and milestones				365,000
Maximum amount of payments receivable for development milestones				70,000
Maximum amount of payments receivable for regulatory milestones				170,000
Maximum amount of payments receivable for sales milestones				80,000
Maximum amount of payment receivable for each additional medicine developed				136,500
Cumulative payments received				150,000
Next prospective payment				15,000
Number of separate performance obligations \| PerformanceObligation	1
Transaction price	$ 30,000
Revenue						$ 35,000
IONIS-FB-L for Complement-Mediated Diseases [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Upfront payment received			$ 75,000
Minimum amount of payments receivable for license fees and milestones				680,000
Cumulative payments received				75,000
Next prospective payment				$ 20,000
Number of separate performance obligations \| PerformanceObligation								1
Transaction price								$ 75,000
Number of disease indications \| Indication				2
Royalty percentage received on net sales of medicine				20.00%
Revenue		$ (9,200)
IONIS-FB-L for Complement-Mediated Diseases [Member] \| GA [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Number of disease indications \| Indication				1
IONIS-FB-L for Complement-Mediated Diseases [Member] \| IgA Nephropathy [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Number of disease indications \| Indication				1