Severance and Retention Costs related to our Restructured Operations (Tables)

12 Months Ended

Dec. 31, 2021

Restructured European Operations [Member]

Severance and Retention Costs [Abstract]

Severance and Retention Costs

The following table summarizes the severance and retention expenses related to our restructured European operations that we recognized for the periods indicated (in millions):

	Year Ended December 31, 2021		Year Ended December 31, 2020
R&D expenses	$	0.6	$	4.2
SG&A expenses		1.1		8.3
Total	$	1.7	$	12.5

The following table summarizes the severance and retention reserve amounts related to our restructured European operations that we included in accrued compensation for the period indicated (in millions):

	Year Ended December 31, 2021
Beginning balance as of January 1, 2021	$	12.4
Amount expensed during the year		2.6
Reserve adjustments during the year		(0.9	)
Net amount expensed during the year		1.7
Amounts paid during the year		(14.1	)
Ending balance as of December 31, 2021	$	—

Restructured North American TEGSEDI Operations [Member]

Severance and Retention Costs [Abstract]

Severance and Retention Costs

The following table summarizes the severance expenses related to our Restructured North American TEGSEDI Operations that we recognized for the period indicated (in millions):

	Year Ended December 31, 2021
R&D expenses	$	2.3
SG&A expenses		7.1
Total	$	9.4

The following table summarizes the severance reserve amounts related to our Restructured North American TEGSEDI Operations that we included in accrued compensation for the period indicated (in millions):

	Year Ended December 31, 2021
Beginning balance as of January 1, 2021	$	—
Net amount expensed during the year		9.4
Amounts paid during the year		(9.4	)
Ending balance as of December 31, 2021	$	—