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CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) (Unaudited) [Abstract]        
Net income (loss) $ (43,091) $ 18,432 $ (145,340) $ 99,304
Unrealized gains (losses) on debt securities, net of tax (3,448) (1,110) 5,803 6,666
Currency translation adjustment 275 (13) 357 (25)
Comprehensive income (loss) (46,264) 17,309 (139,180) 105,945
Comprehensive loss attributable to noncontrolling interests (12,188) (7,731) (33,883) (10,423)
Comprehensive income (loss) attributable to Ionis Pharmaceuticals, Inc. stockholders $ (34,076) $ 25,040 $ (105,297) $ 116,368