-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 UIXQpXu5eqNzjpbA98pBRfiRxERiejMpX/FnoWNqJfpBDQc24eTCtlB4/2SNCnOz
 qV95auY1cnsbosAh8aeOgg==

<SEC-DOCUMENT>0000873591-03-000041.txt : 20030912
<SEC-HEADER>0000873591-03-000041.hdr.sgml : 20030912
<ACCEPTANCE-DATETIME>20030912165228
ACCESSION NUMBER:		0000873591-03-000041
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030912
FILED AS OF DATE:		20030912

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MEDIMMUNE INC /DE
		CENTRAL INDEX KEY:			0000873591
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				521555759
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		35 W WATKINS MILL RD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878
		BUSINESS PHONE:		3014170770

	MAIL ADDRESS:	
		STREET 1:		35 W WATKINS MILL ROAD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BOOTH MELVIN D
		CENTRAL INDEX KEY:			0001219867

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14657
		FILM NUMBER:		03894360

	BUSINESS ADDRESS:	
		STREET 1:		35 W WATKINS MILL ROAD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878
		BUSINESS PHONE:		3014170770

	MAIL ADDRESS:	
		STREET 1:		35 W WATKINS MILL ROAD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>c0001219867d20030912f4f.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<ownershipDocument><schemaVersion>X0201</schemaVersion>    <documentType>4</documentType><periodOfReport>2003-09-12</periodOfReport><notSubjectToSection16>0</notSubjectToSection16><issuer><issuerCik>0000873591</issuerCik><issuerName>MEDIMMUNE INC /DE</issuerName>        <issuerTradingSymbol>MEDI</issuerTradingSymbol></issuer><reportingOwner><reportingOwnerId><rptOwnerCik>0001219867</rptOwnerCik><rptOwnerName>BOOTH MELVIN D</rptOwnerName></reportingOwnerId><reportingOwnerAddress><rptOwnerStreet1>35 WEST WATKINS MILL ROAD</rptOwnerStreet1><rptOwnerStreet2></rptOwnerStreet2><rptOwnerCity>GAITHERSBURG</rptOwnerCity><rptOwnerState>MD</rptOwnerState><rptOwnerZipCode>20878</rptOwnerZipCode><rptOwnerStateDescription></rptOwnerStateDescription></reportingOwnerAddress><reportingOwnerRelationship><isDirector>1</isDirector><isOfficer>1</isOfficer><isTenPercentOwner>0</isTenPercentOwner><isOther>0</isOther><officerTitle>President and COO</officerTitle><otherText></otherText></reportingOwnerRelationship></reportingOwner><
nonDerivativeTable><nonDerivativeTransaction><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-09-12</value></transactionDate><deemedExecutionDate></deemedExecutionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>M</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionTimeliness><value></value></transactionTimeliness><transactionAmounts><transactionShares><value>100000</value></transactionShares><transactionPricePerShare><value>11</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>120035</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership><natureOfOwnership><value></value></natureOfOwnership></ownershipNature></nonDerivativeTransaction><nonDerivativeTr
ansaction><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-09-12</value><footnoteId id="F1"/></transactionDate><deemedExecutionDate></deemedExecutionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>S</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionTimeliness><value></value></transactionTimeliness><transactionAmounts><transactionShares><value>100000</value></transactionShares><transactionPricePerShare><value>37.2684</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>D</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>20035</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership><natureOfOwnership><value></value></natureOfOwnership></ownershipNature></nonDerivativeTransaction></nonDerivativeTable><deri
vativeTable><derivativeTransaction><securityTitle><value>Stock Options (Right to buy)</value></securityTitle><conversionOrExercisePrice><value>11</value></conversionOrExercisePrice><transactionDate><value>2003-09-12</value></transactionDate><deemedExecutionDate></deemedExecutionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>M</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>100000</value></transactionShares><transactionPricePerShare><value>0</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>D</value></transactionAcquiredDisposedCode></transactionAmounts><exerciseDate><value>1999-10-05</value></exerciseDate><expirationDate><value>2008-10-05</value></expirationDate><underlyingSecurity><underlyingSecurityTitle><value>Common Stock</value></underlyingSecurityTitle><underlyingSecurityShares><value>100000</value></underlyingSecurityShares></underlyingSecurity><postTransactionAmou
nts><sharesOwnedFollowingTransaction><value>550000</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership><natureOfOwnership><value></value></natureOfOwnership></ownershipNature></derivativeTransaction></derivativeTable><footnotes><footnote id="F1">This transaction was effected pusuant to a Rule 10b5-1 Sales Plan adopted on August 12, 2003.</footnote></footnotes><ownerSignature><signatureName>Timothy R Pearson</signatureName><signatureDate>2003-09-12</signatureDate></ownerSignature></ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----