Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 1,481,836	$ 1,502,648
Short-term investments	255,997	435,923
Accounts receivable	118,203	101,340
Inventory	240,333	231,961
Other current assets	174,981	213,324
Total current assets	2,271,350	2,485,196
Property and equipment, net	203,107	190,430
Intangible assets, net	14,124	13,628
Right of use assets	65,068	91,761
Other non-current assets	211,584	203,703
Total assets	2,765,233	2,984,718
Current liabilities:
Accounts payable	76,651	111,090
Accrued expenses	180,636	193,553
Deferred revenue, current portion	89,244	89,244
Other current liabilities	18,205	22,139
Total current liabilities	364,736	416,026
Long-term debt	1,091,110	992,493
Lease liabilities, net of current portion	60,675	80,367
Deferred revenue, net of current portion	641,483	663,488
Contingent consideration	50,800	50,800
Other non-current liabilities	20,984	19,785
Total liabilities	2,229,788	2,222,959
Commitments and contingencies (Note 15)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding
Common stock, $0.0001 par value, 198,000,000 shares authorized; 79,748,109 and 79,374,247 issued and outstanding at March 31, 2021, and December 31, 2020, respectively	8	8
Additional paid-in capital	3,490,658	3,609,877
Accumulated other comprehensive (loss) income, net of tax	(3)	3
Accumulated deficit	(2,955,218)	(2,848,129)
Total stockholders’ equity	535,445	761,759
Total liabilities and stockholders’ equity	$ 2,765,233	$ 2,984,718