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Summary of Other Non-current Assets (Detail) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Prepaid Expense And Other Assets Noncurrent [Abstract]    
Manufacturing-related deposits and prepaids $ 122,091 $ 62,821
Strategic investments 31,937 31,739
Restricted cash and investments 9,566 1,001
Prepaid clinical expenses 4,665 7,541
Alternative minimum tax credit 3,367 3,367
Other 2,233 825
Total other non-current assets $ 173,859 $ 107,294