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Summary of Restructuring Costs (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Restructuring Cost And Reserve [Line Items]      
Total restructuring expenses $ (2,222) $ 3,020 $ 4,562
Research and Development [Member]      
Restructuring Cost And Reserve [Line Items]      
Total restructuring expenses   188 2,013
Selling, General and Administrative [Member]      
Restructuring Cost And Reserve [Line Items]      
Total restructuring expenses $ (2,222) $ 2,832 $ 2,549