ACCRUED EXPENSES

12 Months Ended

Dec. 31, 2018

Payables And Accruals [Abstract]

ACCRUED EXPENSES

12. ACCRUED EXPENSES

The following table summarizes the Company’s accrued expenses for each of the periods indicated:

	As of December 31, 2018		As of December 31, 2017
	(in thousands)
Product revenue related reserves	$	26,146	$	7,302
Accrued employee compensation costs		24,692		14,402
Accrued milestone expense		24,020		—
Accrued contract manufacturing costs		15,794		14,019
Accrued clinical and pre-clinical costs		11,396		15,975
Accrued professional fees		11,319		6,794
Accrued BioMarin royalties		8,254		2,846
Accrued property and equipment		5,421		2,525
Accrued collaboration cost sharing		2,167		—
Accrued research costs		1,070		401
Accrued interest expenses		1,045		1,291
Accrued income taxes		301		943
Other		2,470		2,484
Total accrued expenses	$	134,095	$	68,982