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Summary of Other Non-current Assets (Detail) - USD ($)
$ in Thousands
Sep. 30, 2017
Dec. 31, 2016
Prepaid Expense And Other Assets Noncurrent [Abstract]    
Prepaid clinical expenses $ 7,056 $ 3,725
Manufacturing-related deposits 3,570  
Other 362 242
Total other non-current assets $ 10,988 $ 3,967