Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($) shares in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Revenues:
Product, net	$ 16,342,000
Total revenues	16,342,000
Costs and expenses:
Cost of sales	252,000
Research and development	29,119,000	$ 38,826,000
Selling, General and administrative	26,216,000	20,876,000
Total cost and expenses	55,587,000	59,702,000
Operating loss	(39,245,000)	(59,702,000)
Other income (loss):
Gain from sale of Priority Review Voucher	125,000,000
Interest income (expense) and other, net	335,000	(68,000)
Total other income (loss)	125,335,000	(68,000)
Income (loss) before income tax expense	86,090,000	(59,770,000)
Income tax expense	2,000,000	0
Net income (loss)	84,090,000	(59,770,000)
Other comprehensive income:
Unrealized gain on short-term securities - available-for-sale	65,000	106,000
Total other comprehensive income	65,000	106,000
Comprehensive income (loss)	$ 84,155,000	$ (59,664,000)
Net income (loss) per share:
Basic earnings (loss) per share	$ 1.53	$ (1.31)
Diluted earnings (loss) per share	$ 1.50	$ (1.31)
Weighted average number of shares of common stock used in calculating:
Basic earnings (loss) per share	54,850	45,697
Diluted earnings (loss) per share	56,012	45,697