Gain From Sale of Priority Review Voucher - Additional Information (Detail) - USD ($) $ in Thousands		3 Months Ended
Mar. 30, 2017	Mar. 31, 2017
Gain From Sale Of Intangible Asset [Line Items]
Gain from sale of PRV asset		$ 125,000
Gilead [Member]
Gain From Sale Of Intangible Asset [Line Items]
Gain from sale of PRV asset	$ 125,000	$ 125,000

Amount of gain (loss) on sale or disposal of intangible assets.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.7,9)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
-URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3602-108585

Name:	us-gaap_GainLossOnDispositionOfIntangibleAssets
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration