Summarizes Components of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 68,147	$ 61,938
Less: accumulated depreciation	(30,346)	(24,594)
Property and equipment, net	37,801	37,344
Land [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,158	4,158
Building and Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	12,729	12,718
Software and Computer Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	6,775	6,149
Lab Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	14,149	12,873
Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	3,028	2,762
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	22,872	21,723
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 4,436	$ 1,555