-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Dje+W+3YtZDBZFGFmGEfuIIXVKzoN1Sh1gMykeAhH4Xdn/vSekS0slTxCDoTPSsg
 4JiL6pIjHINxGOzvRBY8Hw==

<SEC-DOCUMENT>0001257957-04-000054.txt : 20040405
<SEC-HEADER>0001257957-04-000054.hdr.sgml : 20040405
<ACCEPTANCE-DATETIME>20040405203403
ACCESSION NUMBER:		0001257957-04-000054
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040329
FILED AS OF DATE:		20040405

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AVI BIOPHARMA INC
		CENTRAL INDEX KEY:			0000873303
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				930797222
		STATE OF INCORPORATION:			OR
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE SW COLUMBIA
		STREET 2:		STE 1105
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97258
		BUSINESS PHONE:		5032270554

	MAIL ADDRESS:	
		STREET 1:		ONE SW COLUMBIA
		STREET 2:		SUITE 1105
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97258

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTIVIRALS INC
		DATE OF NAME CHANGE:	19970123

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			OHANLEY PETER D
		CENTRAL INDEX KEY:			0001285527

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14895
		FILM NUMBER:		04719045

	BUSINESS ADDRESS:	
		STREET 1:		6134 NE ALMEDA ST
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97213
		BUSINESS PHONE:		5032881100
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0201</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2004-03-29</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000873303</issuerCik>
        <issuerName>AVI BIOPHARMA INC</issuerName>
        <issuerTradingSymbol>AVII</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001285527</rptOwnerCik>
            <rptOwnerName>OHANLEY PETER D</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>6134 NE ALAMEDA STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PORTLAND</rptOwnerCity>
            <rptOwnerState>OR</rptOwnerState>
            <rptOwnerZipCode>97213</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Sr. Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>2.89</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2005-03-29</value>
            </exerciseDate>
            <expirationDate>
                <value>2014-03-29</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>100000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <ownerSignature>
        <signatureName>Peter D. O'Hanley</signatureName>
        <signatureDate>2004-04-05</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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