Statements of Cash Flows (Unaudited) (USD $) In Thousands, unless otherwise specified	9 Months Ended		386 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012
Cash flows from operating activities:
Net income (loss)	$ (59,220)	$ (908)	$ (369,184)
Adjustments to reconcile net income (loss) to net cash flows used in operating activities:
Depreciation and amortization	1,090	763	21,535
Loss on disposal of assets	182	161	2,453
Realized gain on sale of short-term securities--available-for-sale	0	0	(3,863)
Write-down of short-term securities--available-for-sale	0	0	17,001
Impairment charge on real estate owned	0	109	1,445
Stock-based compensation	1,840	2,454	30,835
Conversion of interest accrued to common stock	0	0	8
Acquired in-process research and development	0	0	29,461
Increase (decrease) on warrant liability	40,154	(25,579)	15,184
(Increase) in accounts receivable, other current assets and other assets	(1,162)	(1,356)	(6,336)
Increase (decrease) in accounts payable, accrued employee compensation, and other liabilities	(5,420)	6,325	8,711
Net cash used in operating activities	(22,536)	(18,031)	(252,750)
Cash flows from investing activities:
Purchase of property and equipment	(108)	(973)	(19,987)
Patent costs	(614)	(548)	(10,106)
Purchase of marketable securities	0	0	(112,993)
Sale of marketable securities	0	0	117,724
Acquisition costs	0	0	(2,389)
Net cash used in investing activities	(722)	(1,521)	(27,751)
Cash flows from financing activities:
Proceeds from sale of common stock, warrants, and partnership units, net of offering costs, and exercise of options and warrants	21,405	32,380	319,283
Repayments of long-term debt	(64)	(61)	(409)
Buyback of common stock pursuant to rescission offering	0	0	(289)
Withdrawal of partnership net assets	0	0	(177)
Issuance of convertible debt	0	0	80
Net cash provided by (used in) financing activities	21,341	32,319	318,488
Increase (decrease) in cash and cash equivalents	(1,917)	12,767	37,987
Cash and cash equivalents:
Beginning of period	39,904	33,589	0
End of period	37,987	46,356	37,987
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid during the year for interest	65	68	554
SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING ACTIVITIES AND FINANCING ACTIVITIES:
Short-term securities--available-for-sale received in connection with the private offering	0	0	17,897
Issuance of common stock and warrants in satisfaction of liabilities	391	643	1,579
Issuance of common stock for building purchase	0	0	750
Assumption of long-term debt for building purchase	0	0	2,200
Issuance of common stock to acquire assets	0	0	8,075
Assumption of liabilities to acquire assets	$ 0	$ 0	$ 2,124