Statements of Cash Flows (Unaudited) (USD $) In Thousands, unless otherwise specified	6 Months Ended		383 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012
Cash flows from operating activities:
Net income (loss)	$ (9,666)	$ 3,112	$ (319,630)
Adjustments to reconcile net income (loss) to net cash flows used in operating activities:
Depreciation and amortization	715	490	21,160
Loss on disposal of assets	123	44	2,394
Realized gain on sale of short-term securities available-for-sale	0	0	(3,863)
Write-down of short-term securities-available-for-sale	0	0	17,001
Impairment charge on real estate owned	0	0	1,445
Stock-based compensation	1,148	1,862	30,143
Conversion of interest accrued to common stock	0	0	8
Acquired in-process research and development	0	0	29,461
Increase (decrease) on warrant liability	(2,562)	(18,527)	(27,532)
(Increase) in accounts receivable, other current assets and other assets	(3,537)	(7,586)	(8,711)
Increase (decrease) in accounts payable, accrued employee compensation, and other liabilities	(952)	10,097	13,179
Net cash used in operating activities	(14,731)	(10,508)	(244,945)
Cash flows from investing activities:
Purchase of property and equipment	(143)	(676)	(20,022)
Patent costs	(498)	(525)	(9,990)
Purchase of marketable securities	0	0	(112,993)
Sale of marketable securities	0	0	117,724
Acquisition costs	0	0	(2,389)
Net cash used in investing activities	(641)	(1,201)	(27,670)
Cash flows from financing activities:
Proceeds from sale of common stock, warrants, and partnership units, net of offering costs, and exercise of options and warrants	1	32,348	297,879
Repayments of long-term debt	(42)	(40)	(387)
Buyback of common stock pursuant to rescission offering	0	0	(289)
Withdrawal of partnership net assets	0	0	(177)
Issuance of convertible debt	0	0	80
Net cash provided by (used in) financing activities	(41)	32,308	297,106
Increase (decrease) in cash and cash equivalents	(15,413)	20,599	24,491
Cash and cash equivalents:
Beginning of period	39,904	33,589
End of period	24,491	54,188	24,491
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid during the year for interest	43	45	532
SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING ACTIVITIES AND FINANCING ACTIVITIES:
Short-term securities--available-for-sale received in connection with the private offering	0	0	17,897
Issuance of common stock and warrants in satisfaction of liabilities	0	644	1,188
Issuance of common stock for building purchase	0	0	750
Assumption of long-term debt for building purchase	0	0	2,200
Issuance of common stock for Ercole assets	0	0	8,075
Assumption of liabilities for Ercole assets	$ 0	$ 0	$ 2,124