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Stock Compensation (Details 3) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Summary of the stock-based compensation expense        
Stock-based compensation expense recognized $ 440 $ 716 $ 1,148 $ 1,862
Research and development [Member]
       
Summary of the stock-based compensation expense        
Stock-based compensation expense recognized 259 359 512 732
General and administrative [Member]
       
Summary of the stock-based compensation expense        
Stock-based compensation expense recognized $ 181 $ 357 $ 636 $ 1,130