Statements Of Cash Flows (USD $) In Thousands	9 Months Ended		379 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011
Cash flows from operating activities:
Net loss and comprehensive loss	$ (908)	$ (24,533)	$ (308,554)
Adjustments to reconcile net loss to net cash flows used in operating activities:
Depreciation and amortization	763	1,053	19,908
Loss on disposal of assets	161	274	2,242
Realized gain on sale of short-term securities-available-for-sale			(3,863)
Write-down of short-term securities-available-for-sale			17,001
Impairment charge on real estate owned	109	393	1,445
Stock-based compensation	2,454	2,540	28,320
Conversion of interest accrued to common stock			8
Acquired in-process research and development			29,461
Increase (decrease) on warrant valuation	(25,579)	5,509	(17,527)
(Increase) decrease in:
Accounts receivable, other current assets and other assets	(1,356)	(3,297)	(5,467)
Net increase in accounts payable, accrued employee compensation, and other liabilities	6,325	4,740	12,460
Net cash used in operating activities	(18,031)	(13,321)	(224,566)
Cash flows from investing activities:
Purchase of property and equipment	(973)	(628)	(19,674)
Patent costs	(548)	(821)	(8,913)
Purchase of marketable securities		(5)	(112,993)
Sale of marketable securities			117,724
Acquisition costs			(2,389)
Net cash used in investing activities	(1,521)	(1,454)	(26,245)
Cash flows from financing activities:
Proceeds from sale of common stock, warrants, and partnership units, net of offering costs, and exercise of options and warrants	32,380	2,525	297,878
Repayments of long-term debt	(61)	(58)	(325)
Buyback of common stock pursuant to rescission offering			(289)
Withdrawal of partnership net assets			(177)
Issuance of convertible debt			80
Net cash provided by financing activities	32,319	2,467	297,167
Increase (decrease) in cash and cash equivalents	12,767	(12,308)	46,356
Cash and cash equivalents:
Beginning of period	33,589	48,275
End of period	46,356	35,967	46,356
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid during the year for interest	68	70	467
SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING ACTIVITIES AND FINANCING ACTIVITIES:
Short-term securities-available-for-sale received in connection with the private offering			17,897
Issuance of common stock and warrants in satisfaction of liabilities	643		1,188
Issuance of common stock for building purchase			750
Assumption of long-term debt for building purchase			2,200
Issuance of common stock for Ercole assets			8,075
Assumption of liabilities for Ercole assets			$ 2,124