Statements Of Cash Flow (USD $) In Thousands	6 Months Ended		376 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011
Cash flows from operating activities:
Net income (loss) and comprehensive income (loss)	$ 3,112	$ (17,240)	$ (304,534)
Adjustments to reconcile net loss to net cash flows used in operating activities:
Depreciation and amortization	490	698	19,635
Loss on disposal of assets	44	237	2,125
Realized gain on sale of short-term securities-available-for-sale			(3,863)
Write-down of short-term securities-available-for-sale			17,001
Impairment charge on real estate owned			1,336
Stock-based compensation	1,862	2,031	27,728
Conversion of interest accrued to common stock			8
Acquired in-process research and development			29,461
Increase (decrease) on warrant valuation	(18,527)	1,931	(10,475)
(Increase) decrease in:
Accounts receivable and other current assets	(7,586)	(143)	(11,697)
Net increase in accounts payable, accrued employee compensation, and other liabilities	10,097	1,938	16,232
Net cash used in operating activities	(10,508)	(10,548)	(217,043)
Cash flows from investing activities:
Purchase of property and equipment	(676)	(340)	(19,377)
Patent costs	(525)	(622)	(8,890)
Purchase of marketable securities			(112,993)
Sale of marketable securities			117,724
Acquisition costs		(3)	(2,389)
Net cash used in investing activities	(1,201)	(965)	(25,925)
Cash flows from financing activities:
Proceeds from sale of common stock, warrants, and partnership units, net of offering costs, and exercise of options and warrants	32,348	19	297,846
Repayments of long-term debt	(40)	(39)	(304)
Buyback of common stock pursuant to rescission offering			(289)
Withdrawal of partnership net assets			(177)
Issuance of convertible debt			80
Net cash provided by (used in) financing activities	32,308	(20)	297,156
Increase (decrease) in cash and cash equivalents	20,599	(11,533)	54,188
Cash and cash equivalents:
Beginning of period	33,589	48,275
End of period	54,188	36,742	54,188
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
Cash paid during the year for interest	45	47	444
SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING ACTIVITIES AND FINANCING ACTIVITIES:
Short-term securities-available-for-sale received in connection with the private offering			17,897
Issuance of common stock and warrants in satisfaction of liabilities	644		1,189
Issuance of common stock for building purchase			750
Assumption of long-term debt for building purchase			2,200
Issuance of common stock for Ercole assets			8,075
Assumption of liabilities for Ercole assets			$ 2,124